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Gut Bacteria and Fat Cells May Interact to Produce “Perfect Storm” of Inflammation That Promotes Diabetes and Other Chronic Disease
by Dr. Mercola
Mercola
A wide array of health problems, including but not limited to obesity, insulin resistance, type 2 diabetes, periodontal disease, stroke, and heart disease all have inflammation as a part of the disease.
The majority of inflammatory diseases start in your gut.
Chronic inflammation in your gut can disrupt the normal functioning of many bodily systems. There also appears to be a connection between certain types of bacteria and body fat that produces a heightened inflammatory response and drives the inflammatory process.
For example, recent research [1] suggests that superantigens—toxic molecules produced by pathogenic bacteria such as staph—may play a role in the development of type 2 diabetes through their effect on fat cells. As reported by the featured article: [2]
“The idea is that when fat cells (adipocytes) interact with environmental agents — in this case, bacterial toxins — they then trigger a chronic inflammatory process… [B]acterial toxins stimulate fat cells to release molecules called cytokines, which promote inflammation…
All staph bacteria make toxins called superantigens — molecules that disrupt the immune system. Schlievert's research has previously shown that superantigens cause the deadly effects of various staph infections, such as toxic shock syndrome, sepsis, and endocarditis.
Source: http://www.riseearth.com/2014/06/gut-bacteria-and-fat-cells-may-interact.html
