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They have been credited for inspiring some of the most popular songs of a generation.
Now scientists claim they are closer to understanding why magic mushrooms cause people to have such intense creative and spiritual experiences.
Scans have revealed that its active ingredient, psilocybin, creates a hyperconnected mind that links regions of the brain that are normally have nothing to do with each other.
Scans have revealed that its active ingredient, psilocybin, creates a hyperconnected mind (right) that links up regions of the brain that normally don’t talk to each other. On the left is how a brain under placebo appears
This triggers vivid hallucinations, often making colours seem oversaturated and breaking up the boundaries between objects.
The increased brain activity could also be responsible for synaesthesia – the phenomenon where different senses are associated with others, according to UK scientists.