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Curejoy Expert Claude Butler Explains:
When you smoke a cigarette, nicotine circulating in the bloodstream gives a kind of high. On an average 6-8 hours is how long the nicotine from a single cigarette lasts. Most of that nicotine will get eliminated in the urine. 48-72 hours is how long it can take for most of the stored nicotine to be metabolized and leave your body. 20-30 days is how long the nicotine by-product cotinine can continue to circulate in the bloodstream.
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