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Schizophrenia and Alzheimer’s disease risk is linked to brain inflammation, according to a study published in the American Journal of Psychiatry. The researchers found that immune cells are more active in the brains of individuals in high-risk group for schizophrenia and Alzheimer’s disease, and who have already been diagnosed with such conditions. The findings point out that early testing for individuals at risk could onset earlier treatment to avoid severe symptoms.
The researchers used positron emission tomography (PET) scans to measure immune cell activity within the brain. These cells – known as microglia – respond to damage and infection in the brain, and are also responsible for rearranging connections between brain cells to ensure they work efficiently. This process is known as pruning.