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Researchers from Ohio State University have discovered that the commonly used pain reliever, acetaminophen, has a previously unknown side effect:
It kills positive emotions.
In the study, participants who took acetaminophen reported feeling fewer strong emotions when they were shown very pleasant or very disturbing photos, compared to those who took placebos.
You might be thinking correlation doesn’t mean causation, but when you use the Bradford Hill criteria, and examine all of the other studies done regarding the psychological effects of over the counter pain killers, the picture becomes clearer. (source)(source)
Acetaminophen is the main ingredient in the commonly used pain reliever Tylenol and has been used for more than 70 years in the United States, but this marks the first time that this “side effect” has been documented. It’s the most common drug ingredient in the United States, found in more than 600 medicines, according to the Consumer Healthcare Products Association. (source)
“In all, rather than being labeled as merely a pain reliever, acetaminophen might be better described as an all-purpose emotion reliever… [and] it is apparent that using acetaminophen for the treatment of pain might have broader consequences than previously thought.” – Geoffrey Durso, lead author of the study and a doctoral student in social psychology at The Ohio State University. (source)
Again, the conclusions of the study suggest that acetaminophen “has a general blunting effect on individuals’ evaluative and emotional processing, irrespective of negative or positive valence.” (source)
This is not the only research that has been conducted on acetaminophen’s effects beyond just mitigating physical pain. Studies have shown that it does indeed have some sort of psychological effect, and as Durso states, “this study takes those results one step further by showing that it also reduces how much users actually feel positive emotions.” (source)
The researchers also mentioned that:
“These results build on recent psychological research illustrating that acetaminophen can blunt the intensity with which individuals experience negative events that originate from physical, social, or cognitive sources (DeWall et al., 2015; DeWall et al., 2010; Randles et al., 2013). Further, these findings expand on the research to date to show that acetaminophen blunts positive evaluations in like fashion.” (source)
It’s also important to note here that the use of pain killers (like aspirin and ibuprofen) has been associated with heart failure risk. A review of 754 clinical trials( published in Lancet) found that pain killers (ibuprofen in particular) have been estimated to be a contributing factor in the deaths of thousands of people each year. According to the lead researcher of that review, long term use of these drugs caused thousands of heart attacks as well as sudden cardiac deaths that occurred between 1999-2003. In this case, the drug Vioxx was singled out. (source)(source)
So, you’re saying, if I have significant heart issues (as I do), I shouldn’t take ibuprofen, particularly if I drink a lot?
I mean why not, last time I went to a clinic with heart issues, the doctor actually prescribed me something that had the issues I complained about as contraindications? Surely a doctor can’t be wrong, following his logic, it seems I MUST TAKE IBUPROFEN.
I can answer that. ibuprofen can be damaging if you have serious heart issues. However, the drinking is a reverse issue, as ibuprofen is less damaging to the gut than aspirin or tylenol. However, tylenol is seriously dangerous in other ways for heavy drinkers.
I would concur with your physician, as the cardiac risk from ibuprofen is outweighed by the benefits. Personally, I still stand by aspirin, it’s the safest one out there, for *most* peoiple,,but if you have issues with your gut such as heavy drinking iit can lead to a bleeding ulcer.. so, not for drinkers, oir anyone with an allergy to aspirin either.
American law requires I specify that none of this is to be taken as medical advice. Yeah, right. Hope the lawyers are happy now ;-(
I knew most of that, actually. My doctor didn’t prescribe me ibuprofen, I simply mentioned it because the article pointed it at as being particularly damaging and I had use some rhetoric about how many doctors are actually just heartless marketers.
Thank you for the reply though.
And excuse my typing errors, I am somewhat inebriated. All day, every day.
I been there
Oh, PS.. you know that true heart issues don’t present as heart pain.. Pain like that is usually sourced from the gut. Watch that one.. I was throwing up blood every morning until I drank about a gallon of cider… I was sure I was going to have a heart attack, but a cardiac trace only showed age related deterioration..
GBY and take care of yourself…
Thank you for your concern but some of my heart issues (though some are physical) aren’t exactly curable, knowm sayn?
Also, a recent study suggested that aspirin is actually quite damaging to the heart (though perhaps not as damaging as to the gut).