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Genentech's Big Worry: Roche?

Thursday, August 23, 2012 8:51
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There’s no telling if this is true – it’s part of a lawsuit. But a former Genentech employee is claiming that the company rushed trials of its PI3K inhibitor. And why? Worries about their partner:


The suit alleges that the Pi3 Kinase team was guilty of “illegal and unethical conduct” by skirting established scientific and ethical standards required of drug researchers. Juliet Kniley claims she complained in 2008 and then was sidelined in 2009 with a demotion after being instructed to push ahead on the study. And she says she was told twice that Roche would “take this molecule away from us” if they saw her proposed timelines.

Genentech denies the allegations. But you have to wonder if there’s still a window here into the relationship between the two companies. . .

Derek Lowe is a medicinal chemist with over 20 years experience in the drug industry. He blogs daily on science and drug discovery at In The Pipeline



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