Vitamin B1 and Thiamine-responsive megaloblastic anemia syndrome
Home of Kyle J. Norton for The Better of Living & Living Health The vitamin B-complex are essential water-soluble vitamins, including vitamin B1(thiamine), vitamin B2 (riboflavin ), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), biotin, folic acid and vitamin B12 (cobalamins).
A. Vitamin B1 (Thiamine)
Vitamin B1 and Thiamine-responsive megaloblastic anemia syndrome
In the study of Thiamine-responsive megaloblastic anemia syndrome: a novel mutation at Dr. Sami Ulus Training and Research Children’s Hospital, Clinics of Pediatric Endocrinology, Ankara, showed that the disease can manifest at any time between infancy and adolescence, and not all cardinal findings are present initially. The anemia typically improves significantly with pharmacological doses of thiamine. Variable improvement in diabetes is also noted. However, the hearing loss is apparently irreversible, although a delay in the onset of deafness may be possible(9).
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Sources
(9) http://www.ncbi.nlm.nih.gov/pubmed/22876572
http://medicaladvisorjournals.blogspot.com
2012-08-26 17:31:59
Source: http://medicaladvisorjournals.blogspot.com/2012/08/vitamin-b1-and-thiamine-responsive.html
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