Macrocytic anemia and vitamin B12 deficiency
Home of Kyle J. Norton for The Better of Living & Living Health The vitamin B-complex are essential water-soluble vitamins, including vitamin B1(thiamine), vitamin B2 (riboflavin ), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), biotin, folic acid and vitamin B12 (cobalamins).
Vitamin B12 (Cobalamins) not only plays an important role in fatty acid synthesis and energy production, but also is essential in the normal functioning of the brain and nervous system, and for the formation of blood.
Macrocytic anemia and vitamin B12 deficiency
Pernicious anemia is a macrocytic anemia due to cobalamin deficiency, which is the result of intrinsic factor deficiency. The management of patients with pernicious anemia should focus on the life-long replacement treatment with cobalamin and the monitoring to early diagnose an eventual onset of iron deficiency. Moreover, these patients should be advised about possible gastrointestinal long-term consequences, such as gastric cancer and carcinoids(15).
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Sources
(15) http://www.ncbi.nlm.nih.gov/pubmed/21947876
http://medicaladvisorjournals.blogspot.com
2012-10-21 13:00:13
Source: http://medicaladvisorjournals.blogspot.com/2012/10/macrocytic-anemia-and-vitamin-b12.html
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