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Vitamin E and diabetic endothelial dysfunction

Friday, November 16, 2012 3:10
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Home of Kyle J. Norton for The Better of Living & Living Health According to the study of Vitamin E: function and metabolism, Vitamin E is the term for a group of tocopherols and tocotrienols, of which α-tocopherol has the highest biological activity(a), and is the most common in the North American diet. 
Vitamin E and diabetic endothelial dysfunction
In the study of twenty-eight rats rendered diabetic by streptozotocin injection and fed either with a diet with low (10 mg/kg of chow), medium (75 mg/kg of chow) or high amounts of vitamin E (1300 mg/kg of chow). Nine age-matched nondiabetic rats receiving 75 mg of vitamin E/kg chow served as controls, the results showed that 1) vitamin E has a potential to prevent partially hyperglycemia-induced endothelial dysfunction, 2) under in vivo conditions vitamin E deficiency enhanced diabetic endothelial dysfunction dramatically, and 3) positive effects of vitamin E may be attenuated with a longer disease duration(36).

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Sources

(36) http://www.ncbi.nlm.nih.gov/pubmed/12649359 

http://medicaladvisorjournals.blogspot.com



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