Thyroid hormone and the cardiovascular system
Home of Kyle J. Norton for The Better of Living & Living Health Thyroid hormone (triiodothyronine (T3) and thyroxine (T4)), produced by the thyroid gland, plays an important role in regulation of metabolism, including directly boosts energy metabolism and triggers rapid protein synthesis and regulates mitochondrial gene transcription, etc. Iodine is necessary for the production of T3 and T4, deficiency of Iodine can lead to enlarge thyroid grand and goitre.
Thyroid hormone and the cardiovascular system
Increased or reduced action of thyroid hormone on certain molecular pathways in the heart and vasculature causes relevant cardiovascular derangements. It is well established that overt hyperthyroidism induces a hyperdynamic cardiovascular state (high cardiac output with low systemic vascular resistance), which is associated with a faster heart rate, enhanced left ventricular (LV) systolic and diastolic function, and increased prevalence of supraventricular tachyarrhythmias – namely, atrial fibrillation – whereas overt hypothyroidism is characterized by the opposite changes.In the study of Effects of thyroid hormone on the cardiovascular system, researchers suggested that
administration of thyroid hormone or its analogue 3,5-diiodothyropropionic acid greatly benefits these patients, highlighting the potential role of thyroid hormone treatment in patients with acute and chronic cardiovascular disease(7).
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Sources
(7) http://www.ncbi.nlm.nih.gov/pubmed/14749496 http://medicaladvisorjournals.blogspot.com
2013-01-07 16:49:58
Source: http://medicaladvisorjournals.blogspot.com/2013/01/thyroid-hormone-and-cardiovascular.html
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