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Vitamin E management of oxidative damage-linked dysfunctions of hyperthyroid tissues

Friday, January 18, 2013 5:22
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Home of Kyle J. Norton for The Better of Living & Living Health Thyroid hormone (triiodothyronine (T3) and thyroxine (T4)), produced by the thyroid gland, plays an important role in regulation of metabolism, including directly boosts energy metabolism and triggers rapid protein synthesis and regulates mitochondrial gene transcription, etc. Iodine is necessary for the production of T3 and T4, deficiency of Iodine can lead to enlarge thyroid grand and goitre.
Vitamin E management of oxidative damage-linked dysfunctions of hyperthyroid tissues
Thyroid hormones affect growth, development, and metabolism of vertebrates, and are considered the major regulators of their homeostasis and elevated circulating levels of thyroid hormones are associated with modifications in the whole organism (weight loss and increased metabolism and temperature) and in several body regions. Indeed, tachycardia, atrial arrhythmias, heart failure, muscle weakness and wasting, bone mass loss, and hepatobiliary complications are commonly found in hyperthyroid animals and humans. In the study of vitamin E and oxdative linked dysfunctions of huperthroid tissues, showed that vitamin E has a primary function to destroy peroxyl radicals, thus protecting polyunsaturated fatty acids biological membranes from oxidative damage. However, results are also available indicating that protective vitamin E effects against oxidative damage can be obtained even through different mechanisms(27).

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Sources 
(27) http://www.ncbi.nlm.nih.gov/pubmed/23255045
  http://medicaladvisorjournals.blogspot.com



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