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Hormone Catecholamines – Epinephrine-containing local anesthesia and cardiovascular disease

Friday, February 15, 2013 15:20
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Home of Kyle J. Norton for The Better of Living & Living Health Hormone Catecholamines, derived from the amino acid tyrosine, produced by the adrenal glands, which are found on top of the kidneys. are epinephrine (adrenaline), norepinephrine (noradrenaline) and dopamine. The hormones are released into the blood during times of physical or emotional stress.
Epinephrine-containing local anesthesia and cardiovascular disease
In the study to examine the safety of epinephrine-containing local anesthesia for use on patients with cardiovascular diseasein twenty-seven patients with cardiovascular disease, showed that Systolic blood pressure and heart rate increased by 4.1% and 5.1%, respectively, immediately after the lidocaine-epinephrine injection. Consequently, rate pressure product increased by 10.0%. Cardiac index increased by 14.2%, and total peripheral resistance decreased by approximately 10%. No patient complained of cardiac symptoms. There were no significant differences in hemodynamic responses related to the extent of the cardiac functional capacity(2).

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Sources
(2) http://www.ncbi.nlm.nih.gov/pubmed/11740477   http://medicaladvisorjournals.blogspot.com



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