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Starvation hormone extends mouse life span by thirty to forty percent

Saturday, October 20, 2012 16:12
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From NextBigFuture.com

A study by UT Southwestern Medical Center researchers finds that a starvation hormone markedly extends life span in mice without the need for calorie restriction.

“Restricting food intake has been shown to extend lifespan in several different kinds of animals. In our study, we found transgenic mice that produced more of the hormone fibroblast growth factor-21 (FGF21) got the benefits of dieting without having to limit their food intake. Male mice that overproduced the hormone had about a 30 percent increase in average life span and female mice had about a 40 percent increase in average life span,” said senior author Dr. Steven Kliewer, professor of molecular biology and pharmacology.

eLife journal – The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

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