New technique can sequence entire genome from single cell

(Before It's News)

From NextBigFuture.com

Researchers have developed a method — dubbed MALBAC, short for Multiple Annealing and Looping-based Amplification Cycles — that requires just one cell to reproduce an entire DNA molecule.

More than three years in the making, the breakthrough technique offers the potential for early cancer treatment by allowing doctors to obtain a genetic “fingerprint” of a person’s cancer from circulating tumor cells. It also could lead to safer prenatal testing for a host of genetic diseases.

Science – Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing

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