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Synthesizing DNA 10,000 times cheaper and making a synthetic biology revolution

Friday, February 15, 2013 0:20
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From NextBigFuture.com

Problem: Synthetic biology has the potential to create new organisms that could do an infinite number of things. But the cost of synthesizing DNA is currently prohibitively expensive.

Solution: Austen has developed a new technique to synthesize DNA 10,000 times cheaper than existing technology.

1. DNA microarray
2. Microbeads capture DNA – separates the sequences
3. Beads copy the single strand many times
4. Attach beads to glass and read out the sequences for quality control and create a quality score
5. Use laser to recover the DNA (Laser pulse catapulting)
Print up to 100 strands per second

B4INREMOTE-aHR0cDovLzQuYnAuYmxvZ3Nwb3QuY29tLy00S0Y5SGFtYWwtdy9VUjNlZHFCQmZKSS9BQUFBQUFBQWlMZy96Z2xEdVFScUFBNC9zMzIwL3N5bnRoZG5hLnBuZw==

Technology: One of the big challenges with DNA synthesis is error correction during fabrication, fabricating the correct sequence of A, T, G and Cs. Austen solves this problem by fabricating billions of strands at once, quickly (and cheaply) optically sequencing them and then selecting the correct DNA sequences using a fast moving laser.

More on SolveforX.com.

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