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Mechanistic insights into EGFR membrane clustering revealed by super-resolution imaging
Wednesday, January 28, 2015 11:59
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Where size matters
Nanoscale , 2015, 7,2511-2519
DOI: 10.1039/C4NR04962D, Paper
Jing Gao, Ye Wang, Mingjun Cai, Yangang Pan, Haijiao Xu, Junguang Jiang, Hongbin Ji, Hongda Wang
We investigate the distribution of membrane EGFR by direct stochastic optical reconstruction microscopy (dSTORM). Our results illustrate the clustering distribution pattern of EGFR in polarized cells and uncover the essential role of lipid rafts in EGFR cluster maintenance.
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Source: http://nanochemistry.blogspot.com/2015/01/mechanistic-insights-into-egfr-membrane_28.html
