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Glutathione- and pH-responsive nonporous silica prodrug nanoparticles for controlled release and cancer therapy
Wednesday, March 11, 2015 6:11
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Where size matters
Nanoscale , 2015, Advance Article
DOI: 10.1039/C5NR00297D, Paper
Zhigang Xu, Shiying Liu, Yuejun Kang, Mingfeng Wang
Stimuli-responsive nonporous silica prodrug nanoparticles are developed by covalently encapsulating anticancer drugs camptothecin (CPT) and doxorubicin (DOX) into silica matrices through glutathione (GSH)-responsive disulfide and pH-responsive hydrazone bonds.
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Source: http://nanochemistry.blogspot.com/2015/03/glutathione-and-ph-responsive-nonporous.html
